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A Strategy to Arrest and Reverse Coronary Artery Disease: A 5-Year Longitudinal Study of a Single Physician’s Practice
Caldwell B. Esselstyn, Jr, MD; Stephen G. Ellis, MD; Sharon V. Medendorp, MPH; and Timothy D. Crowe

At the outset of this study in 1985, patients were told that this type of program might work because of its success in animal studies,2 but the more recent investigations that confirm and illustrate its success in humans cannot be overemphasized. 3-is Although quality-of-life measurements were not a part of this study, all patients indicated less fear of relapse and increased confidence. As they complete a disease-free decade, these patients are empowered by the knowledge that they are in control of the disease that was destroying their lives.

When total serum cholesterol is maintained at less than 150 mg/dL (3.88 mmol/L) with less than 10% fat intake and cholesterol-lowering drugs, this treatment appears to treat not only the symptoms but the cause of heart disease and to prevent its clinical progression, as demonstrated in 100% of the 16 adherent patients in this study. The techniques needed to implement this treatment can be applied in most practices.

Acknowledgments

The authors wish to thank the following individuals for their assistance:
Michael D. Cressman, DO; Jay Hollman, MD; Irving D. Franco, MD; Herbert K. Naito, PhD; Fredric J. Pashkow, MD; Russell E. Raymond, DO; Mebdi Razavi, MD; Earl K. Shirex’, MD; Holly Vilsack; Charlene Tyrrell, MA; and Tom Lang, MA.

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